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Protocols
Meditation Protocol
Based on research with meditation practitioners, this meditation protocol details safe, stepwise use of Low-5—covering preparation, dose, duration…
Jul 3, 2025
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StepWise Protocol
Research into an alternative to high-dose psychedelics where clients gradually self-administer short-acting Low-5 via vape pens, prioritizing autonomy…
Jul 3, 2025
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Low-5 Transforms Group Therapy – A 6-Hour Psycholytic Journey
In a single-day workshop, facilitators used Low-5 to guide participants through therapy, using intention-setting, incremental dosing, and group…
May 23, 2025
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Innovation Interview – StepWise for Safer Psychedelic Journeys
The creator of StepWise opens up about designing gentle psychedelic experiences. The StepWise co-creator explains how Low-5 dosing empowers clients…
Mar 21, 2025
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The First Meditation Protocol for Low Dose 5-MeO-DMT
Our research illustrates how meditation practitioners are using Low-5 to deepen focus and introspection. This harmonized protocol provides a…
Feb 18, 2024
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Low-5 Users Get First-Ever Harm Reduction Guide
Therapists and psychonauts finally have a dedicated Low-5 harm reduction resource. It details safe dosing (<2 mg), vaporization tips, and aftercare…
Dec 18, 2023
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