Low-5’s Discovery Timeline – From Toad to Tek.
Trace the evolution of Low-5 vaporization, from ancient snuffs to modern vape pens.
Early history: There is evidence that indigenous people of South America have used plants containing trace amounts of 5-MeO-DMT for millennia, ingesting it through snuffs.
1936: 5-MeO-DMT first synthesized by chemists Toshio Hoshino and Kenya Shimodaira.
1965: Bufo Alvarius toad skin detected to contain 5-MeO-DMT.
1980s: The use of Bufo Alvarius toad venom, which contains 5-MeO-DMT, spreads in underground psychedelic communities.
2003: The modern vape pen is invented by Hon Lik, a Chinese pharmacist, after his father, a heavy smoker, died of lung cancer.
2012: Majus OneLight (pseudonym) has the idea for vaporizing 5-MeO-DMT (Jaguar) in a dab pen. This leads to…
2015: The first commercial vape pen is filled with 5-MeO-DMT by Dr. Livingston (pseudonym), a medical device specialist.
2018: Grace Within attends a Jaguar retreat (with Majus OneLight).
February 2021: Publication of "Jaguar (5-MeO-DMT) Vape Pens: How They Are Made" by Grace Within on Erowid.org
October 2021: Internet search for meditation and 5-MeO and for microdose 5-MeO get zero results.
February 17, 2022: First known Internet mention of meditation with Five, when Rak Razam mentions doing so at the panel discussion "Futureshock: How 5-MeO-DMT Saved the World."
May 2022: The Entheogenic Evolution Podcast features Rak Razam and the team from Bridging Heaven, on their new silent retreat combining meditation and low-dose Five. The Pattern Project founder, Axle Davids, attends.
June 2023: Unveiling of the Pattern Project at MAPS Psychedelic Science Conference in Denver, Colorado.
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