Why Therapists Are Buzzing About the Low-5 StepWise Protocol

The StepWise protocol stacks multiple Low-5 doses into a single therapeutic process—and early reactions suggest a breakthrough, offering gentle healing in brief, safe-feeling sessions.

StepWise is the first protocol for psychedelic therapy that uses stepped, stacked doses of Low-5 (Low dose 5-MeO-DMT) self-administered by the client using a graduated set of Low-5 vape pens. It introduces client autonomy, real-time dosing adjustments, and shorter sessions, providing a gentler yet effective alternative to traditional high-dose psychedelic-assisted therapy. Pattern Project sources—aboveground and underground—view the StepWise Protocol as a potential game changer.

• The developer of the leading 5-MeO-DMT “handshake, hug, full-embrace” protocol regards StepWise as the natural evolution of his approach and is a leading proponent of this new method.

• One trauma therapist we interviewed shared that she no longer uses MDMA or psilocybin in her practice, calling StepWise a safer, more effective approach.

Could this be the breakthrough we’ve all been waiting for?

Find out why pioneering licensed psychedelic therapists and members of the psychedelic community see StepWise as the next-generation protocol in psychedelic therapy.